Myxobacteria secondary metabolites pdf

Pdf bioassaybased screening of myxobacteria producing. Thus far, no pathogenic myxobacteria have been observed and many bioactive. Their abilities such as gliding motility, predation by producing antibiotics, lytic enzymes. Myxobacteria, producers of novel bioactive substances. During the past 15 years the myxobacteria have been shown in our laboratories to be a rich source of novel secondary metabolites, many of the compounds showing interesting and sometimes unique mechanisms of action.

In a research program at the gesellshaft fur biotechnologische forschung over the past 25 years the organisms have been shown to be a rich source of potentially useful secondary metabolites. Myxobacteria became wellknown as prolific producers of secondary metabolites during the past few decades 37, 38. Myxobacteria are capable of producing secondary metabolites of several chemical classes, many with unique features, exhibiting a wide spectrum of bioactivities, often with novel modes of action reichenbach, 2001. Bioassaybased screening of myxobacteria producing antitumor secondary metabolites wenjie guo1,3, fengjie cui1 and wenyi tao1,2 1school of biotechnology, southern yangtze university. Myxobacteria are prolific producers of secondary metabolites with research into biosynthesis of these compounds focusing on members of the genus sorangium. One way to new compounds is the exploitation of new producer organisms. During the past 15 years the myxobacteria have been shown in our laboratories to be a rich source of novel secondary metabolites, many of the compounds showing interesting and sometimes unique. Myxobacteria have been regarded as microbe factories for active secondary metabolites, and therefore, this study was performed to isolate two bacteriolytic genera of myxobacteria, myxococcus. That is, certain secondary metabolites are only found in one plant species or related group of species, whereas primary metabolites are found throughout the plant kingdom. Biologically active secondary metabolites from myxobacteria. Myxobacteriamicrobial factories for the production of. Myxobacteria are soil bacteria that move by gliding and have an astonishing life cycle culminating in fruiting body formation.